The Burkholderia pseudomallei Type III Secretion System and BopA Are Required for Evasion of LC3-Associated Phagocytosis
Figure 6
The recruitment of LC3 to bacteria-containing phagosomes is diminished in RAW 264.7 cells infected with heat-killed B. pseudomallei.
Quantitative analysis of bacterial co-localization with LC3 in RAW 264.7 cells infected with live B. pseudomallei (wild-type strain, the bopA mutant or the bipD mutant) or heat-killed strains at 2 and 4 h p.i. The data represent the mean ± SEM of three separate experiments (n = 100 bacteria). Where shown * indicates p<0.05 relative to the wild-type strain at each time point.