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Low CD4+ T Cell Counts among African HIV-1 Infected Subjects with Group B KIR Haplotypes in the Absence of Specific Inhibitory KIR Ligands

Figure 2

Effect of KIR and HLA genotypes on the rate of CD4+ T cell decline among HIV-1 infected subjects.

Thin lines represent individual CD4+ T cell count profiles (n = 20). Thick lines represent the fitted models calculated by mixed-effects linear regression analysis. (A) Effects of AA and Bx genotypes. (B) Effect of Bw4:C1 genotype. (C) Effect of Bx genotype in the absence of Bw4:C1. Bw4:C1 denotes the simultaneous occurrence of Bw4 and C1. The estimated fold decrease in CD4+ T cell count per year and p values are shown.

Figure 2

doi: https://doi.org/10.1371/journal.pone.0017043.g002