The Pseudomonas aeruginosa Autoinducer 3O-C12 Homoserine Lactone Provokes Hyperinflammatory Responses from Cystic Fibrosis Airway Epithelial Cells
Figure 4
Heightened induction of IL-6 in IB3-1 by 3O-C12 is antagonized by inhibiting intracellular calcium.
Cells were pre-treated for 1 hr with vehicle or BAPTA-AM (intracellular calcium chelator). Data points are the mean of three independent experiments ± SEM. Statistical significance for comparisons between vehicle and BAPTA-AM within a cell line are indicated with *; comparisons between IB3-1 (vehicle) and C38 (vehicle) are indicated with #; */# p<0.05; **/## p<0.01.