Phosphatidylserine Increases IKBKAP Levels in Familial Dysautonomia Cells
Figure 5
PS alters the cell cycle distribution of FD cells.
One day prior to treatment 750,000 cells were seeded. The cells were treated with 100 µg/ml PS for 24 hr and then fixed and stained with PI according to the flow cytometry protocol. The percentage of cells (A) at the G1 stage and (B) at the growth stages, S+G2, of untreated control, heterozygous, FDA and FDB cells. The percentages of cells at the growth stages, S+G2, of (C) FDA or (D) FDB cells following PS treatment compared to untreated FD cells. All experiments were repeated independently four times, and the results shown are mean values ± SD. P-values of significant results are indicated.