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At What Stage of Neural Processing Does Cocaine Act to Boost Pursuit of Rewards?

Figure 9

Three-dimensional views of the data from Rat 3.

a) Mean time allocation values for the saline condition along with the wire-mesh depiction of the 6-parameter surface fitted to them. The blue and red lines represent the values of the Pe, and Fhm parameters, which determine the position of the 3D structure along the price and frequency axes, respectively. b) 3D representation of the data from the cocaine condition. Note the elevated time allocated to low-frequency trains under the influence of cocaine at low (pink spheres), but not high (dark red spheres), prices. The wire-mesh surface in b) describes the fit of the 7-parameter “conditioned-reward” model to the data.

Figure 9

doi: https://doi.org/10.1371/journal.pone.0015081.g009