Multisite Phosphorylation Provides an Effective and Flexible Mechanism for Switch-Like Protein Degradation
Figure 5
Effects of the number of phosphorylation sites (n) and the threshold for degradation (m).
The response coefficient of the non-degradable fraction for different values of n and m (m varies from 1 to n) are shown for random (A) and sequential (B) processes. System parameters: ,
,
for
and
for
,
,
.