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Transcriptional Reprogramming in Nonhuman Primate (Rhesus Macaque) Tuberculosis Granulomas

Figure 3

Clustering analysis of specific immune categories.

Clustering analysis represents the differences in gene expression in early and late lesions between specific immune categories: chemokines and their receptors (A), cytokines and their receptors (B), IFNγ network (C) and TNF network (D). The coloring scheme is white -no change in expression, blue – lower expression in lesion samples relative to normal lung, and red – higher expression in lesion samples relative to normal lung. Each column represents results obtained from one distinct animal.

Figure 3

doi: https://doi.org/10.1371/journal.pone.0012266.g003