Clinically Relevant Characterization of Lung Adenocarcinoma Subtypes Based on Cellular Pathways: An International Validation Study
Figure 6
Survival differences for different pathologies.
(A) Kaplan-Meier survival analysis of solid lung adenocarcinoma (AD) shows that patients with any solid component do significant worse (p = 0.000166) than those with no solid component. This trend is highly significant (p = 0.00562) in stage 1 patients (B) and marginally significant (p = 0.0295) in stage 3 patients (C). Those patients with any carcinoma in situ (CIS) component (D) did significantly better (p = 0.0342) than those without any CIS component. Comparing patients with papillary component (E) to those without any papillary component showed no significant difference but in stage 3 patients (F) those with some papillary component did significantly better than those without any papillary component. Abbreviations: w/, with; w/o, without.