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Gelsolin Plays a Role in the Actin Polymerization Complex of Hair Cell Stereocilia

Figure 4

Ultrastructural analysis of cochlear outer hair cell stereocilia in gelsolin mutant mice.

Analysis of outer hair cell morphology from P5 to 4 months of age in apical and middle turns in wild-type and gelsolin homozygous knock-out mice (Gsntm1Djk/Gsntm1Djk). Note from P9 stereocilia and bundle morphology in apical turn outer hair cells is abnormal with long thread-like stereocilia appearing from P11. (Scale bar, 10 µm).

Figure 4

doi: https://doi.org/10.1371/journal.pone.0011627.g004