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Methylphenidate Attenuates Limbic Brain Inhibition after Cocaine-Cues Exposure in Cocaine Abusers

Figure 3

SPM results for the Video (Neutral vs Cocaine-cues) by Drug (Placebo vs MP) interaction (MP < PL).

Methylphenidate resulted in less metabolic changes than the Placebo and there were no regions were the differences were greater for Methylphenidate than for the Placebo conditions. Threshold of significance p<0.01 uncorrected, cluster size >200 voxels.

Figure 3

doi: https://doi.org/10.1371/journal.pone.0011509.g003