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Receptor Specificity and Transmission of H2N2 Subtype Viruses Isolated from the Pandemic of 1957

Figure 4

Glycan binding of Alb/58, ElSalv/57, and A/El Salv/57-Q226L viruses.

The binding signals are expressed as percentage of maximum binding of each virus to the glycan arrays. At saturating HA titers, both Alb/58 and A/El Salv/57-Q226L showed binding signals to long and short α2-6 glycans, but Alb/58 also showed high binding signals to long and short α2-3 glycans. ElSalv/57 virus showed binding affinity to all three types of α2-3 glycans but also displayed some binding to long α2-6 glycans at higher titers. The types of glycans used on the arrays are described (Table S2).

Figure 4

doi: https://doi.org/10.1371/journal.pone.0011158.g004