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Novel Snail1 Target Proteins in Human Colon Cancer Identified by Proteomic Analysis

Figure 5

Subcellular distribution of PA2G4.

(A) Representative confocal microscopy images showing the expression and localization of PA2G4 (red) in SW480-ADH Mock and Snail1 cells. GFP expression (green) was unaltered by Snail1 and was used as a control. Scale bar, 5 µm. (B) Representative confocal microscopy images showing double immunolabeling for PA2G4 (red) and for molecular markers (blue) of Cajal bodies (Coilin), Cajal bodies and nuclear speckles of splicing factors (TMG-cap), nucleolus (Fibrillarin), and PML bodies (PML) in SW480-ADH Mock cells. The pink colour in the merge images indicates the existence of colocalization. Scale bar, 5 µm.

Figure 5

doi: https://doi.org/10.1371/journal.pone.0010221.g005