Rapid Biocompatibility Analysis of Materials via In Vivo Fluorescence Imaging of Mouse Models
Figure 2
Time evolution of cathepsin activity in response to injected materials fluorescently imaged.
In vivo fluorescence imaging using ProSense 680 for cathepsin activity at various time points for a) saline, b) polystyrene, and c) alginate. The scale bar ranges 0–6×10−4 in fluorescence efficiency. The quantified fluorescence efficiencies of cathepsin activities are shown for d) polystyrene and e) alginate as the mean with standard deviation. Symbols represent data points and lines represent linear regressions.