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A Novel Analytical Framework for Dissecting the Genetic Architecture of Behavioral Symptoms in Neuropsychiatric Disorders

Figure 2

Pipeline of Algorithm for Behavioral and Genetic Analysis.

a Templeton, A. R., Boerwinkle, E., Sing, C. F. 1987. A cladistic analysis of phenotypic associations with haplotypes inferred from restriction endonuclease mapping. I. Basic theory and an analysis of alcohol dehydrogenase activity in Drosophila. Genetics 117(2):343–351. b Lipscomb DL. 1992. Parsimony, homology and the analysis of multistate characters. Cladistics (8):45–65.

Figure 2

doi: https://doi.org/10.1371/journal.pone.0009714.g002