Neuropeptide Y Knockout Mice Reveal a Central Role of NPY in the Coordination of Bone Mass to Body Weight
Figure 2
Greater cortical bone in NPY −/− mice.
Peripheral quantitative computed tomography of mid-femur in male mice showing (a) total bone volume, (b) marrow volume, (c) cortical bone volume and (d) cortical thickness. (e) Mid femoral endocortical mineral apposition rate, (f) photomicrograph of endocortical bone formation. (g) 24 hour home cage activity. Scale bar represents 50 µm. # p<0.05 vs wild type. n = 8−14, data expressed as mean±SE.