The Use of Knockout Mice Reveals a Synergistic Role of the Vav1 and Rasgrf2 Gene Deficiencies in Lymphomagenesis and Metastasis
Figure 3
The Rasgrf2 gene deficiency does not affect the normal development of T–cells (A) or mature lymphocyte (B) cell numbers.
Bar graphs show the mean percentages of thymocyte (upper panels) and splenic lymphocyte (lower panels) subpopulations derived from animals of the indicated genotypes. Error bars represent the standard deviation (n = 5). *, P<0.01 compared to values obtained with wild type controls.