Genetic Variation in VEGF Does Not Contribute Significantly to the Risk of Congenital Cardiovascular Malformation
Figure 1
Schematic diagram of VEGF based on transcript NM_003376.3; exons are represented as boxes (shaded – coding, unshaded - UTR), introns, up- and down-stream regions as dotted lines; SNPs were selected 15 Kb upstream, within and 15 Kb downstream of VEGF; the location of SNPs is indicated by dashed arrows; the three SNPs in the previously reported haplotype are bracketed; the approximate position of PCR products for sequencing are represented as solid lines with forward (F) and reverse (R) primer pairs indicated; the proportions of exons, introns, up- and down-stream regions are not to scale.