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TRAF6 Is Required for Generation of the B-1a B Cell Compartment as well as T Cell-Dependent and -Independent Humoral Immune Responses

Figure 1

Generation of B cell specific TRAF6 KO mice.

(a) Southern blot analysis to confirm the Cre-mediated deletion of the floxed fragment. (b) Western blot analysis to demonstrate specific deletion of TRAF6 in B cells. Lysates blotted with anti-TRAF6 or anti-actin from B cells and non-B cells are shown.

Figure 1

doi: https://doi.org/10.1371/journal.pone.0004736.g001