Gonadal Transcriptome Alterations in Response to Dietary Energy Intake: Sensing the Reproductive Environment
Figure 3
Gene changes in the gonads of male and female rats maintained on the 20% CR diet compared to the gonads of male and female rats maintained on a control (ad libitum) diet.
Genes that were significantly up-regulated (red) or down-regulated (green) were clustered into a Venn diagram. There were 9 significantly up-regulated and 4 significantly down-regulated genes in the testes collected from 20% CR male rats compared to the genes from testes collected from control (ad libitum) male rats. Ovaries collected from 20% CR female rats showed 33 significantly up-regulated (red) and 10 significantly down-regulated (green) genes compared to control (ad libitum) female rats. There were no common gene alterations between the 20% CR male and female gonadal tissues. Names of the significantly altered genes can be found in Table S1.