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Ultraconserved Elements in the Olig2 Promoter

Figure 1

A) Frequency distribution of potential transcription factor binding sites in 2 Kb windows across the Olig2 upstream region.

Sequences upstream of Olig2 were scanned using Patser [31], [32] for any potential binding site for any of the mammalian transcription factors in TRANSFAC [33]. Total lengths of potential TFBS were summed up for each 2 kb window. B) Frequency distribution of percent identity in the Olig2 promoter. The average percent identity was calculated for every 2 kb window spanning the multiple alignments of sixteen species in the regions upstream of Olig2.

Figure 1

doi: https://doi.org/10.1371/journal.pone.0003946.g001