Etoposide Induces ATM-Dependent Mitochondrial Biogenesis through AMPK Activation
Figure 7
H2O2 treatment increases ATM autophosphorylation, and phosphorylations of p53, AMPK α and ACC (Acetyl-CoA Carboxylase).
HeLa cells were treated with indicated concentrations of H2O2 for 16 hrs followed by cell lysis. Western blottings were performed using antibodies against phosphorylated ATM (Ser1981), p53 (Ser15), AMPK α (Thr172) and ACC (Ser79), respectively.