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Evolutionarily Conserved Protein Sequences of Influenza A Viruses, Avian and Human, as Vaccine Targets

Figure 6

Highly conserved sequences of influenza A viruses in human H1N1, H3N2, H1N2, H5N1, avian H5N1, and other avian subtypes circulating between 1997 and 2006.

A region in the viral proteome is considered as highly conserved when it has identical sequence conservation of at least 9 contiguous amino acids in 80% or more of the protein sequences of the analyzed dataset. The index of virus colored symbol is as shown at the top of the figure.

Figure 6

doi: https://doi.org/10.1371/journal.pone.0001190.g006