Multilevel Deconstruction of the In Vivo Behavior of Looped DNA-Protein Complexes
Figure 4
Effects in gene expression of the free energy of looping for a two-conformation elastic DNA model. Repression levels obtained with Equation 3 using the corresponding free energies of Figure 3. (A) Differences in optimal free energies are varied and the optimal phases are kept fixed. (B, C) Differences in optimal phases are varied and optimal free energies are kept fixed at two different values: 1 kcal/mol (B) and 0 kcal/mol (C).