Protein undernutrition reduces the efficacy of praziquantel in a murine model of Schistosoma mansoni infection
Fig 10
Effects of praziquantel treatment on the liver histology of Schistosoma mansoni-infected mice receiving a low-protein diet.
A, B, C, D E, and F: Hematoxylin-eosin staining A’, B’, C’, D’, E’ and F’: Picrosirius staining. Group IN: infected-untreated mice receiving a standard diet; group IN-PZQ: infected mice receiving a standard diet and treated with praziquantel; group ILP: infected-untreated mice receiving a low-protein diet; group ILP-PZQ: infected mice receiving a low-protein diet and treated with praziquantel. IC: inflammatory cells, Gr: granuloma, O. S.m: egg of S. mansoni, CF: collagen fiber.