Discovery and Characterization of Novel Anti-schistosomal Properties of the Anti-anginal Drug, Perhexiline and Its Impact on Schistosoma mansoni Male and Female Reproductive Systems
Fig 3
Effect of PHX on adult S. mansoni worm couples and on egg production in vitro.
Adult couples were incubated with the indicated doses of PHX and viability and total egg counts assessed as described in the methods section. A) viability curves of adult worm couples; B) total egg counts normalized to worm couples. The mean values ± SEM are shown, the data are representative of three independent experiments. * indicates p values < 0.05, ** indicates p values < 0.01 and *** indicates p values < 0.001.