Characterization of Lethal Zika Virus Infection in AG129 Mice
Fig 5
Brain histopathology after ZIKV infection.
Cortical tissue revealing meningeal infiltration by a mixture of neutrophils and mononuclear cells. A small amount of a similar infiltrate is seen surrounding an adjacent vessel (A). Cerebral neuropil section will cellular pyknosis, scattered neutrophils, and perivascular neutrophilic infiltration (B). Apparent necrosis and neutrophil invasion of primordial germ cell region (C). Scale bar, 20 μm. Data are representative of two independent experiments (n = 4 and 5).