Local Literature Bias in Genetic Epidemiology: An Empirical Evaluation of the Chinese Literature
Figure 2
Meta-Analyses of Gene-Disease Associations in a Large Number of Both Non-Chinese and Chinese Studies
Each study is shown by its odds ratio and 95% confidence intervals (CIs). The box of the point estimate is proportional to the study weight. Also shown are summary estimates by random effects calculations (diamonds). Summary estimates are obtained separately for Chinese studies indexed in PubMed (red), Chinese studies not indexed in PubMed (pink), non-Chinese studies of Asian descent populations (green), and studies of persons of non-Asian descent (blue). An odds ratio of 1 means no genetic effect, odds ratios larger than 1 mean genetic predisposition, and odds ratios less than 1 mean genetic protection.