RAC1 controls progressive movement and competitiveness of mammalian spermatozoa
Fig 6
Effects of RAC1 inhibition on motility parameters of bull sperm.
Box plots (showing the median and first and third quartiles) with whiskers (from minimum to maximum) of average path velocity (VAP) and linearity (LIN) of sperm incubated without (Ct: control) or with different concentrations of NSC23766 (NSC, μM) for 30 min (n = 2186, 2224, 2116 or 2493 sperm for Ct, NSC5, NSC25 or NSC50, respectively) and 60 min (n = 2128, 2092, 2156 or 2572 sperm for Ct, NSC5, NSC25 or NSC50, respectively). For each condition, the percentage of motile sperm (mean ± standard error, n = 7 samples) is also shown (bottom boxes). Statistically significant differences between treatments are indicated by distinct letters (Ps < 0.001).