Leveraging correlations between variants in polygenic risk scores to detect heterogeneity in GWAS cohorts
Fig 7
CLiP heterogeneity scores evaluated over single cohorts in the PGC schizophrenia data set, plotted by the number of genotyped cases.
The black line denotes the expected score given summary statistics reported for schizophrenia and sample sizes specific to each cohort, and colored lines denote z-score thresholds corresponding to particular p-values of significance.