A statistical model for reference-free inference of archaic local ancestry
Fig 1
Outline of the demographic model used for training ArchIE.
We simulate a population starting at size N0 and splitting into archaic and modern human (MH) populations at time T0. The MH population splits into a reference and target population of size N1 and N2, respectively, at time Ts. Then, at time Ta, the archaic population admixes with the target population with an associated admixture proportion m. We use data simulated from this model to train a logistic regression classifier.