MORC2B is essential for meiotic progression and fertility
Fig 3
MORC2B is essential for oogenesis.
(A) Histological analysis of the ovaries from 3-month-old Morc2b+/- and Morc2b-/- females. (B, C) Postnatal loss of oocytes in Morc2b-/- ovaries. Frozen sections from postnatal day 0 (PND0) and 2 (PND2) ovaries were immunostained with anti-YBX2 antibodies. YBX2 is specifically expressed in oocytes [32]. (D) TUNEL analysis of PND0 ovaries. Scale bars: 100 μm (A), 50 μm (B-D).