Genome-Wide Association Study Identifies Nox3 as a Critical Gene for Susceptibility to Noise-Induced Hearing Loss

doi:10.1371/journal.pgen.1005094

Genome-Wide Association Study Identifies Nox3 as a Critical Gene for Susceptibility to Noise-Induced Hearing Loss

Fig 7

Detailed analysis of the 8 kHz frequency stimulus.

Dissection of the 8 kHz frequency by DPOAE I/O function (7A) and ABR wave 1 amplitudes (7B) consistently indicate more impairment in the Nox3^het/Nox3^het and Nox3^het/+ than wild-type. One-way ANOVA (Tukey multiple comparisons). * = p < 0.05. Homozygous = Nox3^het/Nox3^het: Heterozygous = Nox3^het/+: Wild-type = C57BL/6JEiJ strain.

doi: https://doi.org/10.1371/journal.pgen.1005094.g007