Genome-Wide Association Study Identifies Nox3 as a Critical Gene for Susceptibility to Noise-Induced Hearing Loss

doi:10.1371/journal.pgen.1005094

Genome-Wide Association Study Identifies Nox3 as a Critical Gene for Susceptibility to Noise-Induced Hearing Loss

Fig 4

Nox3^het mice have greater PTS (permanent threshold shift) for 8 kHz.

Nox3^het/Nox3^het and Nox3^het/+ display significantly greater PTS in comparison to wild-type controls. Data shown are mean comparisons analyzed by one-way ANOVA (post hoc Tukey test for multiple comparisons). *p < 0.05. Homozygous = Nox3^het/Nox3^het: Heterozygous = Nox3^het/+: Wild-type = C57BL/6JEiJ strain.

doi: https://doi.org/10.1371/journal.pgen.1005094.g004