Hyper-Acetylation of Histone H3K56 Limits Break-Induced Replication by Inhibiting Extensive Repair Synthesis
Fig 7
hst3Δ hst4Δ and pol32Δ mutants are defective in DNA synthesis during gene conversion with a 3.4-kb gap.
A, The TRP1 gene was inserted into MATa-inc on chromosome III in tGI354 to generate tGI354-gap strain. B, Percent survival in isogenic strains with indicated genotypes and/or a 3.4-kb gap. Plotted are the mean values of three independent experiments ± s.d.