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Coordination of Cell Proliferation and Cell Fate Determination by CES-1 Snail

Figure 5

CES-1 binds to an upstream region of the cdc-25.2 locus.

The genome-wide binding sites of the CES-1 protein were identified using ChIP-seq. Shown are the distributions of CES-1-bound regions around the genomic loci of the four cdc-25 genes, whose transcription units are indicated by blue arrows. The black boxes correspond to the gene exons. The red arrow points to the CES-1-bound region upstream of cdc-25.2. Data was visualized using Integrated Genome Browser based on genome WS190 of C. elegans [39].

Figure 5

doi: https://doi.org/10.1371/journal.pgen.1003884.g005