A Germline Polymorphism of DNA Polymerase Beta Induces Genomic Instability and Cellular Transformation
Figure 1
Chromosomal aberrations in P242R-expressing cells.
Representative metaphase spread of MCF10A expressing (A.) WT or (B.) P242R Pol β. Chromosomal fusions are shown with the gray arrow and fragments are shown with black arrows. C. Number of aberrations per metaphase. A total of at least 50 metaphases were scored for each cell line.