Cadm1 Is a Metastasis Susceptibility Gene That Suppresses Metastasis by Modifying Tumor Interaction with the Cell-Mediated Immunity
Figure 5
The effect of Cadm1 expression on tumor and metastasis in athymic mice.
Orthotopic injections of control and Cadm1-expressing cells into athymic nude mice resulted in no significant difference in (a) primary tumor burden, (b) pulmonary metastasis, or (c) tumor-normalized metastasis. (median +/− interquartile range; n = 10 mice per group).