Akirin Links Twist-Regulated Transcription with the Brahma Chromatin Remodeling Complex during Embryogenesis
Figure 1
Akirin mutants display a range of muscle phenotypes.
Lateral views of stage 16 wild-type (ii, wt) and akirin mutant (iii, iv, v) embryos stained with anti-tropomyosin antibodies demonstrate the types of muscle phenotypes observed. All allelic combinations are listed as maternal/paternal contribution. In all figures, anterior is to left and dorsal is up, scale bar = 25 µm. Lateral transverse (LT) muscles are used to illustrate the following predominant muscle defects observed in akirin mutants (red arrows): (iii) missing muscles, (iv) improperly attached muscles, and (v) duplicated muscles. Schematic of wild-type muscle pattern is shown in (i). Penetrance of each defect is given in Table 1.