Stress-Induced PARP Activation Mediates Recruitment of Drosophila Mi-2 to Promote Heat Shock Gene Expression
Figure 1
dMi-2 is recruited to HS genes.
Immunofluorescence (IF) staining of polytene chromosomes with dMi-2, RNA polymerase II (pol IIser2 and pol IIser5), Spt5 antibodies and DAPI as indicated. (A) Untreated chromosomes. Arrows show prominent sites of colocalization. Lower panels show magnified sections of individual chromosome arms. (B) Heat shocked chromosomes. Upper panels show magnified section containing the hsp70 loci 87A and 87C (arrows).