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New Functions of Ctf18-RFC in Preserving Genome Stability outside Its Role in Sister Chromatid Cohesion

Figure 1

Contraction, expansion, and fragility phenotypes of SCC mutants.

For all panels, * denotes p<0.05 and ** designates p<0.01 compared to the respective wild type strain. All assays are described in Table S1. (A) Contraction rates of (CAG)20 and contraction frequencies of (CAG)70, normalized to wild type. (B) Percentage of colonies showing contractions of medium (CAG)70 or long (CAG)155 tracts. (C) Expansions of (CAG)70 tracts, normalized to wild type. (D) Fragility rates with no repeat tract, or with medium (CAG)70 or long (CAG)155 tracts. Error bars denote ± one standard error of the mean (SEM).

Figure 1

doi: https://doi.org/10.1371/journal.pgen.1001298.g001