Selective Constraints in Experimentally Defined Primate Regulatory Regions
Figure 6
Fraction of adaptive substitutions (α) in primate pCRMs and ChIP-chip sequences versus the threshold minor allele frequency (MAF) that was excluded from the analysis prior to the estimation of α (see text).
Confidence intervals are shown as dashed lines and were estimated by bootstrapping the data by case-control region, 10000 times.