Dynamic Reprogramming of DNA Methylation at an Epigenetically Sensitive Allele in Mice
Figure 3
Methylation of the Avy Allele in 12.5-dpc Embryos following Paternal Transmission
The 12.5-dpc embryos produced from an Avy/a sire mated with an a/a dam. Samples were digested and subjected to Southern transfer as described in Figure 1. A range of methylation states were observed, evidenced by the varying amounts of the 9-kb BamHI band remaining after HpaII digestion. This indicates that the methylation is likely to be reset by this stage of development.