Chiral evasion and stereospecific antifolate resistance in Staphylococcus aureus
Fig 3
NADPH anomers in the electron densities.
a. Refinement of α-NADPH (yellow) in the SaDHFR:R-27 crystal structure. Green mesh (difference density) shows unsatisfied electron density. b. Overlay of α-NADPH and t-NADPH (light gray) in the SaDHFR:R-27 crystal structure. c. Refinement of t-NADPH in the SaDHFR:R-27 crystal structure.