Ultrafast population coding and axo-somatic compartmentalization
Fig 3
Impact of initiation site distance and transfer impedance on dynamic gain.
A Phase plots for the AP waveforms at the initiation site. Moving the initiation site away from the soma reduces the lateral current during AP generation, leading to a more rapid initiation dynamics. The local minima of all curves are aligned at (0mV, 0mV/ms). The action potential waveforms are shown in S1 Fig. B Transfer impedance when the stimulus is transmitted from the soma to the AP initiation site. C Increasing xNa to 200μm decreases the high-frequency gain of the neuron model. D Increasing Ra to 750Ωcm reduces the impact of initiation site distance on dynamic gain (compare to Fig 2B). The transfer impedance effect dominates the dynamic gain. A larger xNa reduces the high-frequency gain.