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FilterDCA: Interpretable supervised contact prediction using inter-domain coevolution

Fig 7

Contact map prediction for the interaction between the domain families PF01557 and PF09298 co-occurring in Fumarylacetoacetate (FAA) hydrolases.

The upper panels (A) show the predictions of plmDCA, the lower panels (B) those of FilterDCA, for the first 10, 100 or 1000 predicted contacts. In each figure, the native contacts are shown in grey, TP predictions of the two methods in blue, FP predictions in red. This example shows a case where the plmDCA signal is weak, and consequently cleaning by FilterDCA does lead to a marginal improvement only.

Fig 7

doi: https://doi.org/10.1371/journal.pcbi.1007621.g007