In vitro and in silico multidimensional modeling of oncolytic tumor virotherapy dynamics
Fig 4
HT1080 tdTomato cells (red) were infected with MVeGFP (MOI = 1) and imaged every 15 minutes starting 24 hours post infection (A). Representative images are shown in (A) to (F). From an initial focus (A), the virus spread by syncytium formation to incorporate the bulk of the tumor population over the course of 42 hours.