Gap junction plasticity as a mechanism to regulate network-wide oscillations
Fig 4
Gap junction plasticity lets networks recover synchronization.
For all panels, the x-axis represents the number of cross-network gap junctions between GN and SN. The y-axis represents the difference of resonance frequency between the GN and the SN. The gap junctions are static from panels A to D and plastic from panels E to H. Values for the Gamma Network (resp. Slow Network) are represented by the lower (upper) triangles. The GN (SN) has weak (strong) initial mean GJ coupling. Shared GJs are initialized with mean coupling strength in the middle between those of the GN and the SN. (A) Oscillation power. The GN, with weak GJ coupling, shows weak or no oscillations. (B) Oscillation frequency. We observe that the GN and the SN oscillate at the same frequency only for high number of shared GJs. (C) Phase differences between PAs of the GN and the SN (as for Fig 3H). The GN and the SN stay mostly out-of-phase. (D) Correlation of the PAs of the GN and the SN. Except for the particular case where Δfres = 0 and the number of shared GJs is high, the PAs of the GN and the SN show no correlation. (E) Oscillation power. Comparing with panel A, we observe that the oscillation power seems to match in both networks, with mostly the oscillation power of the GN (initially weak) increasing to the SN’s levels (initially strong). (F) Oscillation frequency. Comparing with panel B, we observe an extension of the region where the GN and the SN oscillate at the same frequency. (G) Phase differences between PAs of the GN and the SN. We observe here a large region where the GN and SN are in-phase. (H) Correlation of the PAs of the GN and the SN. Comparing with panel D, we observe a large extension of the region where both networks are synchronized.