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Improving pairwise comparison of protein sequences with domain co-occurrence

Fig 11

HMM/HMM comparison of new domain families vs. Pfam-B domain families.

Each point is associated with one of our HMMs and corresponds to the best alignment found between this HMM and all Pfam-B HMMs. The x-axis shows the overlap ratio of the local alignment between the two HMMs; the y-axis indicates the negative log. of the alignment p-value; blue line corresponds to y = −log(10−10); while the red line corresponds to x = 0.8.

Fig 11

doi: https://doi.org/10.1371/journal.pcbi.1005889.g011