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A composite network of conserved and tissue specific gene interactions reveals possible genetic interactions in glioma

Fig 1

Gene co-expression score surfaces.

General representation of the regions of interest for differential co-expression relationship scores C, S, and D. Here, ρ1 and ρ2 denote the Spearman rank-correlation of the expression of a given gene pair under condition 1 and condition 2, respectively. Colored regions correspond the three kinds of co-expression: blue is conserved C (strong co-expression in both conditions, no sign change), green is specific S (strong co-expression under only one condition), red is differentiated D (strong co-expression in both conditions, but with opposite signs). The colored letters indicate the scores associated with each colored region.

Fig 1

doi: https://doi.org/10.1371/journal.pcbi.1005739.g001