Improving 3D Genome Reconstructions Using Orthologous and Functional Constraints
Fig 3
Minimal reproduction of the complete dataset.
The bars in the figure denote the minimal amount of data required to reproduce the results obtained using the complete dataset in Fig 2. The minimal degree of sparseness is the one that for all models with equal or larger datasets we were unable to reject the null hypothesis that the median of values was equal to that of the complete dataset (Wilcoxon two-tail rank sum at 0.01 significance level). In most cases (10 out of 15), 5% of the data sufficed to reproduce the result observed for 100%. Choosing a significance threshold of 0.05 affected only model similarity and Irr1p (minimal data: 100% and 50%, respectively).